Abstract Cost- and energy-efficient long-term storage of excess solar energy remains a major bottleneck in the transition to a sustainable society. Here, we present a water-soluble redox-active copolymer containing viologen moieties that can be charged with electrons upon visible light irradiation using…
The nitrile (–C 00000000000000000 00000000000000000 00000000000000000 01111111111111110 00000000000000000 01111111111111110 00000000000000000 01111111111111110 00000000000000000 00000000000000000 00000000000000000 N) functional group is a versatile pharmacophore motif that also serves as an intrinsic,…
Erschienen: The Royal Society of Chemistry, 2026-01-09
Uneven illumination affects all images acquired by optical microscopes, especially large, multicolour and nonlinear measurements. Although removal is possible with various algorithms, evaluating raw and processed images is challenging due to the lack of established workflows for image quality assessment.…
The electrical membrane voltage ( V m ) characterizes the functional state of biological cells, thus requiring precise, noninvasive V m -sensing techniques. While voltage-dependent fluorescence intensity changes from genetically encoded voltage indicators (GEVIs) indicate V m changes, variability in…
Washington, DC: American Chemical Society, 2025-11-22
Functional materials, with their specific properties and functions, are instrumental in advancing technological applications across diverse fields such as biomedicine, energy, aerospace, and electronics. To drive innovation in these materials, it is essential to understand their molecular and structural…
Erschienen: The Royal Society of Chemistry, 2025-11-04
Abstract Nonlinear spectroscopic imaging techniques such as coherent Raman scattering (CRS) have proven to be powerful tools for biomedical research, providing multifaceted imaging data that holds great potential for medical diagnostics and therapy. Among these, broadband implementations such as broadband…
This study demonstrates a hydrolysis‐free approach for characterizing acetalated dextran derivatives using Raman spectroscopy combined with two‐dimensional correlation spectroscopy (2D‐COS). Traditional methods like 1 H‐NMR spectroscopy rely on hydrolysis and are constrained by the time‐sensitive detection…
Cell death programs such as apoptosis and ferroptosis are associated with aberrant redox homeostasis linked to lipid metabolism and membrane function. Evidence for cross-talk between these programs is emerging. Here, we show that cytotoxic stress channels polyunsaturated fatty acids via lysophospholipid…
The spatiotemporal assessment of tissue dynamics after the introduction of disruptive factors is crucial for evaluating their impact and for developing effective countermeasures. Here, we report a 4D-spatiotemporal imaging approach using second harmonic generation (SHG) imaging microscopy, enabling an…
Columbus, Ohio: American Chemical Society, 2025-02-14
Summary Photosynthetic protists, named microalgae, are key players in global primary production. The green microalga Chlamydomonas reinhardtii is a well‐studied model organism. In nature, it dwells in acetate‐rich paddy rice soil, which is not mimicked by standard liquid laboratory conditions. Here,…
Raman spectroscopy (RS) and especially surface-enhance Raman spectroscopy (SERS) applications are useful for detection of disease-related markers and cancer diagnosis. Development of spectral acquisition protocols for spectroscopic measurements of body fluids such as saliva, serum and cerumen are pivotal…
This article presents a versatile method for the preparation of smart interpenetrating polymer networks (IPNs). Based on two different orthogonal binding motives, IPNs are generated by simply mixing ligand containing polymers and corresponding metal salts leading to a polymeric material featuring shape-memory…
Cambridge: The Royal Society of Chemistry, 2024-12-05
Here we present a highly customisable image-based fuzzy logic control (FLC) method for pressure-driven droplet microfluidics. The system is designed to position droplets of different sizes in microfluidic chips of varying channel size in the centre of the region of interest (ROI) using two parallel multiple…
Cerumen, commonly known as earwax, is a complex mixture composed of secretions from ceruminous glands. These secretions are heterogeneous mixtures mainly composed of lipids and proteins. Despite its prevalence, the potential diagnostic value of cerumen remains largely unexplored. Here, we present an…
Cambridge: The Royal Society of Chemistry, 2024-09-18
Cholesterol is an important lipid playing a crucial role in mediating essential cellular processes as well as maintaining the basic structural integrity of biological membranes. Given its vast biological importance, there is an unabated need for sophisticated strategies to investigate cholesterol-mediated…
Erschienen: The Royal Society of Chemistry, 2024-08-07
Abstract Raman spectroscopy was used to study the complex interactions and morphogenesis of the green seaweed Ulva (Chlorophyta) and its associated bacteria under controlled conditions in a reductionist model system. Integrating multiple imaging techniques contributes to a more comprehensive understanding…
There is growing need to utilise Earth-abundant transition metal complexes in photovoltaic and photocatalytic applications, while reducing the current heavy reliance on rare, expensive and toxic heavy transition metal complex, such as Ru-based. Iron is the most abundant transition metal within the same…
The aim of this work was to investigate the possible applications of CARS technology for temperature and concentration measurements in harsh environments (e.g. in combustion and gasification gasification diagnostics) with three different concepts: CARS based on a reliable ps laser system with OPA, CARS…
For the progress of point-of-care medicine, where individual health status can be easily and quickly monitored using a handheld sensor, saliva serves as one of the best-suited body fluids thanks to its availability and abundance of physiological indicators. Salivary biomarkers, combined with rapid and…
In this contribution we review recent developments and advances in femtosecond laser ablation, with a focus on biomedical applications. In recent years, research has focused on further expanding the use of ultrafast laser ablation beyond ophthalmology, addressing needs in other fields such as dental…