(1) Background: Rapid microglial proliferation contributes to the complex responses of the innate immune system in the brain to various neuroinflammatory stimuli. Here, we investigated the regulatory function of phosphoinositide 3-kinase γ (PI3Kγ) and reactive oxygen species (ROS) for rapid proliferation…
Microglial cells represent the macrophages of the brain. During fetal development precursor cells invade into the brain and differentiate to adult microglia cells. Microglial cells differ from circulating macrophages, but they exhibit similar surface receptors and reaction patterns. Disturbances of the…