Objectives: Lung transplantation is a life-saving option for patients with end-stage lung diseases, yet immunosuppression management remains challenging. Induction therapy with interleukin-2 receptor antagonists (IL2-AR), such as basiliximab and daclizumab, is designed to reduce acute rejection and improve…
Zusammenfassung Die koronare CT-Angiographie (koronare CTA) bietet eine hohe diagnostische Genauigkeit zum Nachweis oder Ausschluss obstruktiver Stenosen bei Patienten mit niedriger bis mittlerer Vortestwahrscheinlichkeit. Die diagnostische Genauigkeit hängt jedoch entscheidend von hoher Bildqualität…
Abstract Background We investigated the international mini-mitral registry (MMIR) for differences in minimally-invasive access for surgery on the mitral and tricuspid valve. We compared direct vision with partially or fully endoscopic approaches. Methods From 2015 to 2021, 7,513 consecutive patients…
Die Vorstellung, am Herzen operiert zu werden, mag für viele beängstigend sein. Die Narkose, der Schnitt – und das an unserem lebenswichtigen Organ. Allerdings hat sich die Herzchirurgie enorm weiterentwickelt. Bei vielen Eingriffen sind minimal-invasive OP-Methoden mittlerweile Standard. Minimal-invasiv…
Background: Total arterial revascularization (TAR) may improve outcomes in patients with ischemic cardiomyopathy and heart failure with reduced ejection fraction (HFrEF). Methods: We retrospectively screened 574 adults with HFrEF (LVEF < 40%) undergoing isolated CABG across four German centers (2017–2023).…
Objectives To investigate outcomes of aortic valve replacement with the largest available Epic Supra bioprosthesis (size 29). Methods We reviewed all patients who received an Epic Supra bioprosthesis between 2011 and 2023 and selected all 29 size prostheses that were implanted either into patients with…
Background Delayed device embolization is a rare but dangerous complication after transcatheter edge-to-edge repair (TEER). Case summary A 79-year-old man with acute decompensated severe structural mitral regurgitation underwent TEER with 2 clips after failed medical attempts at recompensation. Six days…
Washington, DC: American College of Cardiology, 2025
Background : Aortic valve infective endocarditis (AV-IE) and mitral valve infective endocarditis (MV-IE) are often grouped together as one entity: left-sided endocarditis. However, there are significant differences between the valves in terms of anatomy, physiology, pressure, and calcification tendency.…
Background/Objectives: The demographic shift towards an aging population necessitates a reevaluation of surgical interventions like coronary artery bypass grafting (CABG) in octogenarians. This study aims to elucidate the outcomes of CABG in octogenarians with heart failure and reduced ejection fraction…
Background The use of extracorporeal life support (ECLS) in patients after surgical repair for acute type A aortic dissection (ATAAD) has not been well documented. Methods We performed a systematic review and meta-analysis to assess the outcomes of ECLS after surgery for ATAAD with data published by…
Objective: Minimally invasive cardiac surgery (MICS) is increasing worldwide. In most cases, the surgical technique includes cannulation of the groin for the establishment of cardiopulmonary bypass, requiring a second surgical incision (SC) for exposure and cannulation of the femoral vessels. With the…
Background: Infective endocarditis represents a life‐threatening disease with high mortality rates. A fraction of patients receives exclusively conservative antibiotic treatment due to their comorbidities and high operative risk, despite fulfilling criteria for surgical therapy. The aim of the present…
Objective: This study assesses predictors for postoperative delirium (POD) and ICU stay durations in HFrEF patients undergoing CABG, focusing on ONCAB versus OPCAB surgical methods. Summary Background Data: In cardiac surgery, especially CABG, POD significantly impacts patient recovery and healthcare…
(1) Background : The use of extracorporeal membrane oxygenation (ECMO) in low cardiac output states after cardiac surgery may aid in patient recovery. However, in some patients, the clinical state may worsen, resulting in multiple organ failure and high mortality rates. In these circumstances, calculating…
Objectives: Benefits of tricuspid valve repair (TVR) in left ventricular assist device (LVAD) patients have been questioned. High TVR failure rates have been reported. Remaining or recurring TR was found to be a risk factor for right heart failure (RHF). Therefore, we assessed our experience. Methods:…
Background: The timely initiation of extracorporeal membrane oxygenation (ECMO) is crucial for providing life support. However, delays can occur when perfusionists are not readily available. The Jena Method aims to address this issue by offering a wet-primed ECMO system that can be rapidly established…
Exercise capacity has been related to morbidity and mortality. It consists of an inherited and an acquired part and is dependent on mitochondrial function. We assessed skeletal muscle mitochondrial function in rats with divergent inherited exercise capacity and analyzed the effect of exercise training.…
Background : This retrospective multicenter study investigates the impact of obesity on short-term surgical outcomes in patients with heart failure and reduced ejection fraction (HFrEF) undergoing coronary artery bypass grafting (CABG). Given the rising global prevalence of obesity and its known cardiovascular…
BACKGROUND: Antithrombotic therapy (ATT) in patients with infective endocarditis (IE) is challenging. OBJECTIVES: The authors evaluated the impact of anticoagulant and antiplatelet therapy on clinical endpoints in IE patients. METHODS: We performed a systematic review and meta-analysis comparing IE patients…