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Article / ChapterCC BY 4.0Wed Feb 8 2023

The Sodium-Glucose Co-Transporter 2 (SGLT2) Inhibitor Empagliflozin Reverses Hyperglycemia-Induced Monocyte and Endothelial…

Semo, Dilvin / Obergassel, Julius / Dorenkamp, Marc / et.al.
aus: Journal of Clinical Medicine : open access journal
Purpose: Hyperglycaemia-induced oxidative stress and inflammation contribute to vascular cell dysfunction and subsequent cardiovascular events in T2DM. Selective sodium-glucose co-transporter-2 (SGLT-2) inhibitor empagliflozin significantly improves cardiovascular mortality in T2DM patients (EMPA-REG…
Basel: MDPI, 2023-02-08
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Article / ChapterCC BY 4.0Fri Feb 3 2023

Pharmacological Targeting of the RAGE-NFκB Signalling Axis Impedes Monocyte Activation under Diabetic Conditions through…

Dorenkamp, Marc / Nasiry, Madina / Semo, Dilvin / et.al.
aus: Cells : open access journal
Monocytes play a vital role in the development of cardiovascular diseases. Type 2 diabetes mellitus (T2DM) is a major CVD risk factor, and T2DM-induced aberrant activation and enhanced migration of monocytes is a vital pathomechanism that leads to atherogenesis. We recently reported the upregulation…
Basel: MDPI, 2023-02-03
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