Staphylococcus aureus (S. aureus) is a very versatile opportunistic human pathogen. Besides an asymptomatic colonisation of humans, it can cause a multiplicity of infections, which vary in severity. By investigating a possible connection between certain pathologies and bacterial phenotypes, general and...
The opportunistic fungal pathogen Candida albicans colonizes mucosal surfaces of the majority of healthy human individuals. However, the fungus can cause superficial infections in otherwise healthy people and could develop life-threatening systemic candidiasis in immunocompromised patients. Mucosal epithelial...
Candida albicans is a polymorphic fungus that colonizes mucosal tissue, and is thus a frequent member of the human microbiome. While it is no threat to healthy individuals, C. albicans can become pathogenic in immunocompromised hosts, being one of the most common human fungal pathogens, and one of the...
The opportunistic fungal pathogen Candida albicans frequently occurs as commensal in the gastrointestinal tract of humans. While it is known that intestinal epithelial cells are highly sensitive to ischemia-reperfusion (IR) injury, the exact role of oxygen for IR-mediated fungal translocation has however...
Coxiella burnetii ist ein obligat intrazelluläres zoonotisches Bakterium, welches Auslöser des Q-Fiebers beim Menschen ist. Es verfügt über ein weites Wirtsspektrum, wobei Wiederkäuer die Hauptinfektionsquelle darstellen. Coxiellen werden über Kot, Milch oder plazentale Produkte ausgeschieden. Die Übertragung...