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Dual PI3K/mTOR inhibitor NVP-BEZ235 enhances radiosensitivity of head and...

aus: Cancers
The PI3K/Akt/mTOR pathway is frequently altered in human papillomavirus (HPV)-positive and negative squamous cell carcinoma of the head and neck (HNSCC) and overstimulation is associated with poor prognosis. PI3K drives Akt activation and constitutive signaling acts pro-proliferative, supports cell...
Basel: MDPI, 2020-02-18