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Dissertation
2012-04-18

In vivo Hypoxia and Aspergillus fumigatus pathogenesis

Aspergillus fumigatus is a ubiquitous mold found in soil and organic debris that is currently the most frequent cause of airborne invasive fungal infections in immunocompromised individuals. In this study the hypothesis that hypoxia is a stress faced in vivo by A. fumigatus and that the ability to sense,...