3 Dokumente gefunden

Physicochemical aspects of pharmaceutically‐relevant polymers and nanoparticles in solution

Pharmapolymers, colloids, and self-assembled systems for biomedical purposes have gained significant importance in the last decades. Besides innovative synthesis routes and formulation techniques, the characterization of these multicomponent systems is of great importance to obtain an insight into their…

Ethoxy acetalated dextran-based nanocarriers accomplish efficient inhibition of leukotriene formation by a novel FLAP antagonist…

Leukotrienes are pro-inflammatory lipid mediators generated by 5-lipoxygenase aided by the 5-lipoxygenase-activating protein (FLAP). BRP-201, a novel benzimidazole-based FLAP antagonist, inhibits leukotriene biosynthesis in isolated leukocytes. However, like other FLAP antagonists, BRP-201 fails to effectively…
Cham (ZG): Springer International Publishing, 2021-12-31

Incentives of using the hydrodynamic invariant and sedimentation parameter for the study of naturally- and synthetically-based…

The interrelation of experimental rotational and translational hydrodynamic friction data as a basis for the study of macromolecules in solution represents a useful attempt for the verification of hydrodynamic information. Such interrelation originates from the basic development of colloid and macromolecular…
Basel: MDPI, 2020-01-31