18 Dokumente gefunden
Psychological distress among individuals with a suicide attempt or suicidal ideation and suicide attempts patterns : first…
The COVID-19 pandemic and related restrictions may have led to increased stress, particularly in people with mental health problems. Since stress factors play important role in the emergence of suicide attempts (SA) and suicidal ideation (SI), they may have been exacerbated by the pandemic, which could…
Implicit and explicit sense of agency in individuals with obsessive-compulsive tendencies
Introduction The sense of agency (SoA), or the perception of control over one’s actions and their outcomes, has been proposed to be attenuated in individuals with obsessive–compulsive disorder (OCD) and obsessive–compulsive (OC) tendencies. According to the Sense of Agency and Seeking Proxies for Internal…
Lausanne: Frontiers Research Foundation, 2025-12-05
Emotion-focused vs. cognitive interventions of schema therapy for borderline personality disorder : effects on neural emotion…
Abstract Background While the effects of psychotherapy methods are being intensively researched, little is known about the clinical and neurobiological effects of specific psychotherapeutic interventions. This study examines the effects of experiential emotion-focused and cognitive interventions in schema…
London: BioMed Central, 2025-11-13
Transdiagnostic alterations in white matter microstructure associated with suicidal thoughts and behaviours in the ENIGMA…
Previous studies have suggested that alterations in white matter (WM) microstructure are implicated in suicidal thoughts and behaviours (STBs). However, findings of diffusion tensor imaging (DTI) studies have been inconsistent. In this large-scale mega-analysis conducted by the ENIGMA Suicidal Thoughts…
London: Nature Publishing Group, 2025-10-24
Prädiktion von und Intervention nach suizidalem Verhalten
Suizide und Suizidversuche sind weltweit ein gravierendes Gesundheitsproblem mit tiefgreifenden Folgen für Betroffene, Angehörige und Gesellschaft. Laut WHO starben 2019 etwa 700.000 Menschen durch Suizid; in Deutschland wurden 2022 mehr als 10.000 Fälle registriert, während jährlich 100.000–200.000…
Untersuchung der funktionellen Konnektivität im fronto-striatalen System mit funktioneller resting-state MRT und deren Assoziation…
Jedes Jahr versterben auf der ganzen Welt ca. 700.000 Menschen aufgrund eines Suizids und etwa 20-mal so viele Menschen versuchen, ihr Leben vorsätzlich zu beenden. Das Wissen über demografische und klinische Risikofaktoren ist bislang ungeeignet, um suizidales Verhalten vorherzusagen. Die Identifizierung…
Psychological distress among individuals with a suicide attempt or suicidal ideation and suicide attempts patterns: first…
Background The COVID-19 pandemic and related restrictions may have led to increased stress, particularly in people with mental health problems. Since stress factors play important role in the emergence of suicide attempts (SA) and suicidal ideation (SI), they may have been exacerbated by the pandemic,…
Lausanne: Frontiers Media S.A., 2024-03-08
Impact of Toxoplasma gondii and Human Microbiome on Suicidal Behavior: A Systematic Review
Background: Suicide remains a persistent global health challenge, resisting widespread prevention efforts. According to previous findings, toxoplasmosis is particularly associated with altered decision making, which could lead to risk-taking behavior, thereby increasing the likelihood for suicidal behavior…
Basel: MDPI, 2024-01-19
Facial expressions of pain: the role of the serotonergic system
aus: Psychopharmacology
Rationale Although interest in the neurobiology of facial communication of pain has increased over the last decades, little is known about which neurotransmitter systems might be involved in regulating facial expressions of pain. Objectives We aim to investigate whether the serotonergic system (5-HT),…
Berlin Heidelberg: Springer, 2023-09-07
Altered brain dynamic in major depressive disorder: state and trait features
Abstract Temporal neural synchrony disruption can be linked to a variety of symptoms of major depressive disorder (MDD), including mood rigidity and the inability to break the cycle of negative emotion or attention biases. This might imply that altered dynamic neural synchrony may play a role in the…
London: Nature Publishing Group, 2023-07-17
Association of the delayed changes in glutamate levels and functional connectivity with the immediate network effects of…
Abstract Ketamine shows rapid antidepressant effects peaking 24 h after administration. The antidepressant effects may occur through changes in glutamatergic metabolite levels and resting-state functional connectivity (rsFC) within the default mode network (DMN). A multistage drug effect of ketamine…
London: Nature Publishing Group, 2023-02-16
Neural Correlates of Impaired Cognitive Control in Individuals with Methamphetamine Dependence : An fMRI Study
aus: Brain Sciences
Impaired cognitive and behavioral control has often been observed in people who use methamphetamine (MA). However, a comprehensive understanding of the neural substrates underlying these impairments is still lacking. The goal of the present study was to study the neural correlates of impaired cognitive…
Basel: MDPI, 2023-01-24
Neurokognitive Performanz von Patienten mit Hypersomnolenzen zentralnervösen Ursprungs
Die Verwendung von neurokognitiven Parametern zur Diagnostik der Hypersomnolenzen zentralnervösen Ursprungs ist bislang kein Usus in der Diagnostik von exzessiver Tagesschläfrigkeit. Aufgrund der theoretischen Grundlagen neurobiologischer Regelkreise ist davon auszugehen, dass der verringerte cerebrospinale…
Relapse Prevention Intervention after Suicidal Event (RISE): Feasibility study of a psychotherapeutic short-term program…
Recent research suggests that treating only mental disorders may not be sufficient to reduce the risk for future suicidal behavior in patients with a suicide attempt(s). It is therefore necessary to pay special therapeutic attention to past suicidal acts. Thus, the newly developed RISE (Relapse Prevention…
Lausanne: Frontiers Media S.A., 2022-07-22
Altered resting-state functional connectome in major depressive disorder: a mega-analysis from the PsyMRI consortium
Major depressive disorder (MDD) is associated with abnormal neural circuitry. It can be measured by assessing functional connectivity (FC) at resting-state functional MRI, that may help identifying neural markers of MDD and provide further efficient diagnosis and monitor treatment outcomes. The main…
London: Nature Publishing Group, 2021-10-07
Functional network alterations differently associated with suicidal ideas and acts in depressed patients: an indirect support…
The transition from suicidal ideas to a suicide act is an important topic of research for the identification of those patients at risk of acting out. We investigated here whether specific brain activity and connectivity measures at rest may be differently associated with suicidal thoughts and behaviors.…
London: Nature Publishing Group, 2021-02-04
8. Vorlesung (01.12.2020): Zwangsstörungen
Vorlesungsinhalt: Zwangsgedanken ("obsessions"); Merkmale; Diagnose; Verteilung der Symptome; Epidemiologie; Komorbiditäten; Genetik; Neurobiologie der Zwangsstörung; Psychotherapie; Wirksamkeit der Behandlung
5. Vorlesung (18.11.2020): Suizidalität
Vorlesungsinhalt: Begriffsklärung; Ursachen, Modelle; Risikoabschätzung; Beurteilung der Suizidalität; Therapie