As first part of an ongoing prospective feasibility trial (DRKS00028114) this work explored the integration of in vivo Raman spectroscopy (RS) into the routine setting workflow of head and neck cancer (HNC) surgery. In vivo RS was performed intraoperatively on 30 patients with HNC cell carcinoma and…
London: Macmillan Publishers Limited, part of Springer Nature, 2025-07-07
Simple Summary: Our study describes a novel approach that combines hyperspectral imaging and deep learning, validated with histopathological ground truth, to enable rapid and accurate delineation of tumor margins in head and neck cancer surgeries. We present a system that acquires spectral data from…
Background : In vivo visualization of malignant tumors remains the main challenge during head and neck cancer surgery. This can result in inadequate tumor margin assessment and incomplete tumor resection, adversely affecting patient outcomes. Hyperspectral imaging (HSI) is a promising approach to address…
Environmental pollution caused by plastic is a present problem. Polystyrene is a widely used packaging material (e.g., Styrofoam) that can be broken down into microplastics through abrasion. Once the plastic is released into the environment, it is dispersed by wind and atmospheric dust. In this study,…
Differences between the sexes exist in many diseases, and in most cases, being a specific sex is considered a risk factor in the development and/or progression. This is not quite so clear in diabetic kidney disease (DKD), the development and severity of which depends on many general factors, such as…
Renal fatty acid (FA) metabolism is severely altered in type 1 and 2 diabetes mellitus (T1DM and T2DM). Increasing evidence suggests that altered lipid metabolism is linked to tubulointerstitial fibrosis (TIF). Our previous work has demonstrated that mice with reduced MORG1 expression, a scaffold protein…