Extracellular vesicles (EVs), including small EVs (sEVs), are involved in neuroinflammation and neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis. Yet, increased neuroinflammation can also be detected in the aging brain, and it is associated…
Senescent cells are cells which lost their proliferation potential but are hyperfunctional and secrete many potentially detrimental cytokines and growth factors. Senescence of macrophages, so called macroph-aging, seems to be especially involved in several age-related diseases like Alzheimer or atherosclerosis.…