1D data, such as time series, and spectroscopy contain rich information but pose challenges for machine learning, due to limited large, labeled datasets and absence of specialized pretrained neural networks. Existing 1D analysis methods often rely on traditional chemometric approaches and rarely exploit…
Abstract Nonlinear spectroscopic imaging techniques such as coherent Raman scattering (CRS) have proven to be powerful tools for biomedical research, providing multifaceted imaging data that holds great potential for medical diagnostics and therapy. Among these, broadband implementations such as broadband…
AI-powered image analysis is a transformative technology with immense potential to enhance diagnostics and patient care. Accurate medical image assessment plays a crucial role in disease detection and treatment planning, yet challenges arise due to noise and visual variations in medical imaging. Image…
Data fusion aims to provide a more accurate description of a sample than any one source of data alone. At the same time, data fusion minimizes the uncertainty of the results by combining data from multiple sources. Both aim to improve the characterization of samples and might improve clinical diagnosis…
Raman spectroscopy is a promising spectroscopic technique for microbiological diagnostics. In routine diagnostic, the differentiation of pathogens of the Enterobacteriaceae family remain challenging. In this study, Raman spectroscopy was applied for the differentiation of 24 clinical E. coli , Klebsiella…
Content: Photonics for the unment medical need; Photonic technologies; Data life cycle and machine learning; Photonic Data Science; Artifical Intelligence; Feature extraction; Dimension reduction; Example of spectral scans; MALDI spectrometric imaging data preprocessing; Raman spectroscopy for sepsis…
Abstract In recent years, we have seen a steady rise in the prevalence of antibiotic-resistant bacteria. This creates many challenges in treating patients who carry these infections, as well as stopping and preventing outbreaks. Identifying these resistant bacteria is critical for treatment decisions…
Biochemical information from activated leukocytes provide valuable diagnostic information. In this study, Raman spectroscopy was applied as a label-free analytical technique to characterize the activation pattern of leukocyte subpopulations in an in vitro infection model. Neutrophils, monocytes, and…
In the presented work, several data fusion and machine learning approaches were explored within the frame of the data combination for various measurement techniques in biomedical applications. For each of the measurement techniques used in this work, the data was ana-lyzed by means of machine learning.…