Background/Objectives : Posterior tarsal tunnel syndrome is a compressive neuropathy of the tibial nerve at the level of the ankle within the tarsal tunnel. However, there is no established gold standard for the diagnosis of tarsal tunnel syndrome to date. High-resolution ultrasound could add important…
Eine neue therapeutische Option für Patienten mit ischämischem Schlaganfall könnte die retrograde elektrische Stimulation des Nervus petrosus major und/oder des Nervus petrosus minor darstellen. Diese Stimulation könnte die Blutzirkulation im Gehirn verbessern und so die Schädigung des betroffenen Hirngewebes…
Zusammenfassung Hintergrund Sepsis ist eine akut lebensbedrohliche multiple Organdysfunktion, ausgelöst durch eine Infektion. Methodik Bei der vorliegenden Leitlinie handelt es sich um ein Update der S3-Leitlinie „Sepsis – Prävention, Diagnose, Therapie und Nachsorge“ (AMWF-Register-Nr.: 079–001) der…
Zentrales Ziel der Dissertation war die Überprüfung der diagnostischen Aussagekraft von drei sonographischen Parametern (Nervenquerschnittsfläche am Karpaltunneleingang, Wrist-to-Forearm Ratio und Wrist-to-Forearm Difference) für die Diagnostik des Karpaltunnelsyndroms bei Patienten mit Diabeteserkrankung…
Background The hepatitis E virus (HEV) can cause acute viral hepatitis with or without neurological manifestations, and occasionally progresses to chronic infection in immunocompromised individuals. The management of chronic HEV infection in cancer patients may be challenging due to the complex immunological…
Muscle ultrasound is a valuable non-invasive and cost-effective method in assessing muscle mass and structure, both of which are significant indicators for the development of sarcopenia and frailty in elderly individuals. Sarcopenia refers to the loss of muscle mass and strength that occurs with age,…
Abstract Background Hoffmann’s syndrome is a rare form of hypothyroid myopathy in adults, which is mainly characterized by muscular weakness and muscular pseudohypertrophy. Case presentation We report about a 61-year-old Western European man with myalgia, myxedema and pseudohypertrophy of the calf muscles.…
Intensive care unit-acquired weakness (ICUAW) is one of the most common causes of muscle atrophy and functional disability in critically ill intensive care patients. Clinical examination, manual muscle strength testing and monitoring are frequently hampered by sedation, delirium and cognitive impairment.…
Abstract Capturing disease progression in amyotrophic lateral sclerosis (ALS) is challenging and refinement of progression markers is urgently needed. This study introduces new motor unit number index (MUNIX), motor unit size index (MUSIX) and compound muscle action potential (CMAP) parameters called…
London: Macmillan Publishers Limited, part of Springer Nature, 2023-03-09
Background and Objectives : Diagnostic ultrasound of the vagus nerve has been used to examine different polyneuropathies, and it has been suggested to be useful as a marker of autonomic dysfunction in diabetic patients. Materials and Methods : We analyzed the cross-sectional area (CSA) of the right vagus…
Hintergrund: Die Aufrechterhaltung des Gleichgewichts ist ein Prozess, der durch die zentrale Integration visueller, vestibulärer und somatosensorischer Informationen koordiniert wird. Es ist unklar, ob das Gehör mit den räumlich-akustischen Informationen ebenfalls zur Aufrechterhaltung des Gleichgewichts…
Aging is a complex process characterized by several molecular and cellular imbalances. The composition and stability of the neuronal cytoskeleton is essential for the maintenance of homeostasis, especially in long neurites. Using human skin biopsies containing sensory axons from a cohort of healthy individuals,…
The neurophysiological technique motor unit number index (MUNIX) is increasingly used in clinical trials to measure loss of motor units. However, the heterogeneous disease course in amyotrophic lateral sclerosis (ALS) obfuscates robust correlations between clinical status and electrophysiological assessments.…
London: Macmillan Publishers Limited, part of Springer Nature, 2022-09-26
Background: Dizziness is a common complaint in older adults. To know which factors are instrumental in enabling patients with chronic dizziness to tolerate their symptoms to a certain degree in everyday life can help to develop tailored therapies. Methods: Data from 358 patients with chronic dizziness…
Lausanne: Frontiers Research Foundation, 2022-07-14
Background: Vertigo and dizziness are common in community-dwelling people and can be treated in specialized multidisciplinary settings. To develop tailored interventions, however, we have to explore risk factors for favorable and unfavorable outcomes. Methods: We prospectively investigated patients with…
Background Vertigo and dizziness are common in older adults. We describe self-reported healthcare utilization because of dizziness and vertigo in older adults attending a tertiary care specialized vertigo center. Methods Data from 765 patients (45% were ≥60 years old) with chronic dizziness and vertigo…
Das Guillain-Barré-Syndrom (GBS) ist eine akute Entzündung des peripheren Nervensystems. Es zeigt sich in symmetrisch aufsteigenden Lähmungen. Auslöser für ein GBS sind beispielsweise bestimmte Erreger oder die 1976/77er Impfung gegen die Influenza A/H1N1. Ziel dieser Studie war es, die Einstellung ehemaliger…