19 Dokumente gefunden

From Validation to Refinement : Optimising a Diagnostic Score for Atypical Lipomatous Tumours and Lipomas

Background/Objectives : Differentiating atypical lipomatous tumours (ALT) from lipomas remains challenging, as both share similar clinical and radiological features but require different forms of management. We previously proposed a clinical–radiological score integrating routine parameters to improve…
Basel: MDPI, 2025-12-14

Geographic Disparities in Survival After Surgery for Metastatic Bone Disease : A Retrospective Analysis from a German Sarcoma…

aus: Cancers
Simple Summary Metastatic bone disease is an important challenge in orthopaedic oncology, as improved cancer survival leads to more patients requiring surgery for skeletal stabilisation. Prognostic factors such as tumour type or pathological fractures are well known. Still, the influence of socio-economic…
Basel: MDPI, 2025-11-15

Are we underestimating pathological fracture risk in malignant bone lesions of the proximal humerus?

Abstract Objective This study is aimed at evaluating the distribution of metastatic bone disease (MBD), with a particular focus on the humerus, and its association with pathological fractures. Factors for contributing to the underestimation of fracture risk were assessed, including their impact on surgical…
Berlin: Springer Berlin Heidelberg, 2025-08

Atypical Lipomatous Tumours vs. Lipomas: A Multimodal Diagnostic Approach

Background/Objectives : This study aimed to develop a reliable scoring system combining clinical and radiological parameters to distinguish atypical lipomatous tumours (ALTs) from lipomas, improving diagnostic accuracy and reducing expensive molecular pathology testing. Methods : A retrospective analysis…
Basel: MDPI, 2025-06-17

Prognostic impact of oligometastases in orthopaedic surgery for metastatic bone disease

Introduction: The rising number of cancer patients with metastatic bone disease (MBD) reflects advancements in treatment. The concept of oligometastatic disease, associated with improved prognosis, has emerged. This study evaluated prognostic factors, including oligometastases, in patients undergoing…
London, England: SAGE Publications, 2025-02-18

05 - Zuckersüße Babys

Es gibt Frauen, die entwickeln während ihrer Schwangerschaft einen sogenannten Gestationsdiabetes. Und es gibt Frauen, die leiden schon vor ihrer Schwangerschaft an Diabetes mellitus. Egal, wie der Fall liegt: Bestens versorgt sind Schwangere dann in unserem Kompetenzzentrum „Diabetes & Schwangerschaft“.…
Jena: Universitätsklinikum, 2024-05-24

SPAM—sub partual analgesia with meptazinol: a prospective cohort study comparing intramuscular with intravenous administration

Purpose: Safe and effective analgesia sub partu is one of the central issues in optimizing vaginal delivery birth experiences. Meptazinol is a common opiate approved for treating labor pain in the first stage of labor. According to the manufacturer, manual meptazinol can be applied intramuscularly or…
Berlin: Springer, 2024-05

Disease Perception and Mental Health in Pregnancies with Gestational Diabetes—PsychDiab Pilot Study

(1) Background: The aim of this work is to investigate the extent to which pregnant women’s well-being is burdened by the diagnosis of gestational diabetes, as well as their sensitivities and illness perceptions. Since gestational diabetes is associated with mental disorders, we hypothesized that the…
Basel: MDPI, 2023-05-09

Obesity during Pregnancy and SARS-CoV-2/COVID-19-Case Series of the Registry Study “COVID-19 Related Obstetric and Neonatal…

(1) Background: Obesity is an increasing challenge in the care of pregnant women. The aim of our study was to investigate whether obesity is an independent risk factor for severe maternal and neonatal outcomes in pregnant women with COVID-19. (2) Methods: Data from the COVID-19 Related Obstetric and…
Basel: MDPI, 2023-03-07

Using flash glucose monitoring in pregnancies in routine care of patients with gestational diabetes mellitus: a pilot study

Aim Flash glucose monitoring (FGM) has been approved for the care of pregnant women with preexisting diabetes since 2017. However, its use in gestational diabetes (GDM) has been critically discussed. Inaccuracy and missing recommendations for target values are the main arguments against the use of FGM…
Mailand: Springer, 2023-02-25

Untersuchung von Behandlungs- und Managementstrategien in der Betreuung von Schwangerschaften mit Gestationsdiabetes : Status…

Der Gestationsdiabetes mellitus (GDM) ist mit ca. 10 % betroffenen Schwangeren die häufigste Schwangerschaftskomplikation. Die vorliegende Arbeit gibt einen Überblick über bisher tatsächlich erzielte Behandlungserfolge einer leitlinienkonformen Therapie. Exemplarisch werden dazu die Behandlungsdaten…

Predictors of a successful vaginal delivery in women with type 1 diabetes: a retrospective analysis of 20 years

Abstract Purpose To evaluate the independent factors associated with the success of a trial of vaginal birth (TVB) in women with type 1 diabetes. Despite all therapeutic efforts and technological innovations, rates of caesarean sections (CS) in pregnant women with type 1 diabetes remain unchanged above…
Berlin: Springer, 2022-06

Predictors of treatment requirements in women with gestational diabetes : a retrospective analysis

The diagnosis of gestational diabetes is usually very stressful for pregnant women, especially because they fear that insulin treatment may become necessary. Knowledge about personal risk factors predicting the probability of insulin treatment could therefore help to improve acceptance of the diagnosis…
Basel: MDPI, 2021-09-27

Circadian rhythm and gestational diabetes: : working conditions, sleeping habits and lifestyle influence insulin dependency…

Objective; Management of gestational diabetes (GDM) is currently changing toward a more personalized approach. There is a growing number of GDM patients requiring only a single dose of basal insulin at night to achieve glucose control. Well-known risk factors like obesity, parity and family history have…
Mailand: Springer, 2021-09

Awareness of euglycaemic diabetic ketoacidosis during pregnancy prevents recurrence of devastating outcomes: : a case report…

Background: Euglycaemic diabetic ketoacidosis (DKA) during pregnancy is a life-threatening obstetric emergency. It requires early identification and prompt action. Obstetricians’ knowledge about symptoms, diagnostic pitfalls and management during pregnancy and delivery need to be improved. We report…
London: BioMed Central, 2021-08-12

Contributing factors to perinatal outcome in pregnancies with gestational diabetes : What matters most? A retrospective analysis

The aim of diabetes care of pregnant women with gestational diabetes mellitus (GDM) is to attain pregnancy outcomes including rates of large-for-gestational-age (LGA) newborns, preeclampsia, C-sections (CS) and other neonatal outcomes similar to those of the non-GDM pregnant population. Obesity and excessive…
Basel: MDPI, 2021-01-18

NUT midline carcinoma in a young pregnant female : a case report

Introduction: The NUT midline carcinoma is a rare tumor mostly reported in the midline of upper aerodigestive tract and mediastinum. Children as well as adolescents are affected without a gender distribution. A standard treatment is not established. So far, there exists no reported case of a pregnant…
London: BioMed Central, 2020-11-07

The relevance of fetal abdominal subcutaneous tissue recording in predicting perinatal outcome of GDM pregnancies : a retrospective…

Guidelines on the management of gestational diabetes (GDM) instruct physicians to involve ultrasound-based monitoring of fetal growth in addition to blood glucose. So far, glucose control besides clinical parameters like maternal body mass index (BMI) and gestational weight gain have been shown to predict…
Basel: MDPI, 2020-10-21

Einfluss der Progressiven Muskelrelaxation auf Schwangerschaft und Geburt : eine prospektive Untersuchung

Obwohl Entspannungsverfahren ein integraler Bestandteil der psychosomatischen Geburtsvorbereitung sind, gibt es nur wenige Studien, welche den Einfluss der Progressiven Muskelrelaxation (PMR) auf Schwangerschaft und Geburt untersucht haben. Die vorliegende Studie umfasst insgesamt 100 Schwangere: 50…