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[4.3.1]Bicyclic FKBP Ligands Inhibit Legionella Pneumophila Infection by Lp Mip‐Dependent and Lp Mip‐Independent Mechanisms

Legionella pneumophila is the causative agent of Legionnaires’ disease, a serious form of pneumonia. Its macrophage infectivity potentiator (Mip), a member of a highly conserved family of FK506‐binding proteins (FKBPs), plays a major role in the proliferation of the gram‐negative bacterium in host organisms.…
Weinheim: Wiley-VCH, 2023-11-02