5 Dokumente gefunden

Rationale and design of the randomized ‘early ventricular assist device’ : Trial (VAD‐DZHK3)

Aims Bridge to transplantation (BTT) with durable, continuous‐flow left ventricular assist devices (LVAD) of patients is a well‐established treatment concept in patients awaiting heart transplantation (HTx). However, the role of elective LVAD implantation in patients with less advanced HF, but increased…
Chichester: Wiley, 2025-09-21

Real-world multicentre cohort study on choices and effectiveness of immunotherapies in NMOSD and MOGAD

Background: Recurrent attacks in neuromyelitis optica spectrum disorders (NMOSDs) or myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) can lead to severe disability. We aimed to analyse the real-world use of immunotherapies in patients with NMOSD and MOGAD, focusing on changes in…
Berlin: BMJ Publishing Group Ltd, 2024-12-27

Percutaneous repair of moderate‐to‐severe or severe functional mitral regurgitation in patients with symptomatic heart failure:…

ABSTRACT Aim The RESHAPE‐HF2 trial is designed to assess the efficacy and safety of the MitraClip device system for the treatment of clinically important functional mitral regurgitation (FMR) in patients with heart failure (HF). This report describes the baseline characteristics of patients enrolled…
Oxford, UK: John Wiley & Sons, Ltd., 2024-07-24

Planning preclinical confirmatory multicenter trials to strengthen translation from basic to clinical research : a multi-stakeholder…

Clinical translation from bench to bedside often remains challenging even despite promising preclinical evidence. Among many drivers like biological complexity or poorly understood disease pathology, preclinical evidence often lacks desired robustness. Reasons include low sample sizes, selective reporting,…
London: BioMed Central, 2022-11-07

Impact of COVID-19 outbreak on regional STEMI care in Germany

Abstract Aims To assess the impact of the lockdown due to coronavirus disease 2019 (COVID-19) on key quality indicators for the treatment of ST-segment elevation myocardial infarction (STEMI) patients. Methods Data were obtained from 41 hospitals participating in the prospective Feedback Intervention…
Berlin: Springer, 2020-12