The detection and quantification of coupling strength and direction are important aspects for achieving a deeper understanding of physiological regulatory processes in the field of network physiology. Due to the limitations of established approaches, we developed directionality indices based on simple…
Lausanne: Frontiers Research Foundation, 2025-02-13
Background: Healthcare professionals in hospitals are exposed to a high level of professional stress, time pressure, workload, and often times poor organizational support. This makes them especially susceptible to burnout. In this pragmatic randomized controlled trial, we test the hypothesis that participation…
Im Bereich der Zeitreihenanalyse richtet sich das Interesse zunehmend darauf, wie Einblicke in die Interaktions- und Regulationsprozesse von pathophysiologischen- und physiologischen Zuständen erlangt werden können. Neuste Fortschritte in der nichtlinearen Dynamik, der Informationstheorie und der Netzwerktheorie…
In today's fast-paced society, chronic stress has become an increasing problem, as it can lead to psycho-physiological health problems. University students are also faced with stress due to the demands of many courses and exams. The positive effects of mindfulness-based stress reduction (MBSR) on stress…
Idiopathic pulmonary fibrosis (IPF) is a chronic and restrictive disease characterized by fibrosis and inflammatory changes in lung tissue producing a reduction in diffusion capacity and leading to exertional chronic arterial hypoxemia and dyspnea. Furthermore, clinically, supplemental oxygen (SupplO…
The purpose of this exploratory study was to determine whether liver dysfunction can be generally classified using a wearable electronic nose based on semiconductor metal oxide (MOx) gas sensors, and whether the extent of this dysfunction can be quantified. MOx gas sensors are attractive because of their…
Impaired heart rate- and respiratory regulatory processes as a sign of an autonomic dysfunction seems to be obviously present in patients suffering from schizophrenia. Since the linear and non-linear couplings within the cardiorespiratory system with respiration as an important homeostatic control mechanism…
Lausanne: Frontiers Research Foundation, 2020-06-16
The multivariate analysis of coupling pathways within physiological (sub)systems focusing on identifying healthy and diseased conditions. In this study, we investigated a part of the central-autonomic-network (CAN) in 17 patients suffering from schizophrenia (SZO) compared to 17 age–gender matched healthy…
Die Bedeutung der autonomen Regulation des Herz-Kreislauf-Systems wurde in
verschiedenen klinischen Studien, die sich auf die erweiterte Diagnostik
und prognostische Risikoerkennung von Patienten mit kardiovaskulären
Krankheiten fokussiert haben, bereits vielfach nachgewiesen. Bisherige
Analysen beschränkten…
Patients suffering from schizophrenia have an increased mortality risk due to cardiovascular events that might be associated with cardiac autonomic dysfunction. The aim of this study was to analyse the interdependencies between indices of autonomic regulation from heart rate and blood pressure variability,…
Das Ziel der vorliegenden Arbeit bestand darin, den Einfluss von atherosklerotischen Gefäßveränderungen auf die autonome Regulation von Herzfrequenz und Blutdruck zu untersuchen, da theoretisch eine Erhöhung der Gefäßsteifigkeit, einerseits über die Beeinflussung der Barorezeptorsensibilität und andererseits…
Heart rate variability (HRV) is a marker of autonomous activity in the heart. An important application of HRV measures is the stratification of mortality risk after myocardial infarction. Our hypothesis is that the information entropy of HRV, a non-linear approach, is a suitable measure for this assessment.…
Während der Schwangerschaft wird die maternale kardiovaskuläre Regulation auf die Bedürfnisse der Versorgung von Mutter und Kind angepasst. Die Analyse der Variabilität und Interaktion von Herzfrequenz und Blutdruck erlaubt eine Quantifizierung dieser Veränderungen. Im Rahmen einer klinischen Studie…