Abstract Background COVID-19 continuously causes severe disease conditions and significant mortality. We evaluate whether easily accessible biomarkers can improve risk prediction of severe disease outcomes. Methods Our study analysed 426 COVID-19 patients collected by German CAPNETZ and PROGRESS study…
Community-acquired pneumonia (CAP) is a major global health concern as it is a leading cause of morbidity, mortality and economic burden to the health care systems. In Germany, more than 15,000 people die every year from CAP. Climate change is altering weather patterns, and it may influence the probability…
Abstract Purpose This study assessed the frequency, clinical significance, and risk factors for Herpes simplex virus (HSV) reactivation in immunocompetent patients with community-acquired pneumonia (CAP). Methods The study included adult CAP-patients who were enrolled in the CAPNETZ study between 2007…
Community-acquired pneumonia (CAP) is one of the most frequent causes of death among infectious diseases worldwide. There is a growing concern about weather impacts on CAP. However, no studies have examined the effects of comorbidities and personal characteristics alongside the twofold impact of weather…
Objectives The objective of this study was to identify the pathogen spectrum of community acquired pneumonia in people living with HIV (PLWH), and to compare it with a matched HIV negative group in order to reassess therapeutic strategies for PLWH. Methods Seventy-three (n = 73) PLWH (median CD4 3–6…
Nanopore sequencing represents a breakthrough in DNA analysis technology, offering a novel approach to genome sequencing through the passage of DNA molecules through nanopores. This method captures distinctive electrical signals from DNA bases, enabling rapid sequence reconstruction in near real-time.…
Purpose Reported antibiotic use in coronavirus disease 2019 (COVID-19) is far higher than the actual rate of reported bacterial co- and superinfection. A better understanding of antibiotic therapy in COVID-19 is necessary. Methods 6457 SARS-CoV-2-infected cases, documented from March 18, 2020, until…