Zusammenfassung Hintergrund Sepsis ist eine akut lebensbedrohliche multiple Organdysfunktion, ausgelöst durch eine Infektion. Methodik Bei der vorliegenden Leitlinie handelt es sich um ein Update der S3-Leitlinie „Sepsis – Prävention, Diagnose, Therapie und Nachsorge“ (AMWF-Register-Nr.: 079–001) der…
Purpose: Timely and accurate data on the epidemiology of sepsis are essential to inform policy decisions and research priorities. We aimed to investigate the validity of inpatient administrative health data (IAHD) for surveillance and quality assurance of sepsis care. Methods: We conducted a retrospective…
Purpose: To investigate whether (1 → 3)-β-d-Glucan (BDG)-guidance shortens time to antifungal therapy and thereby reduces mortality of sepsis patients with high risk of invasive Candida infection (ICI). Methods: Multicenter, randomized, controlled trial carried out between September 2016 and September…
Abstract Background Albumin is a key regulator of fluid distribution within the extracellular space and has several properties beyond its oncotic activity. The accumulating evidence suggests that supplementation of albumin may provide survival advantages only when the insult is severe as in patients…