Background/Objectives : The increasing use of radiopharmaceuticals in clinical practice has raised concerns regarding potential radiation exposure for healthcare personnel handling biological samples from treated patients. The objective of this study was to assess the radioactivity levels in clinically…
Die Leber ist ein multidimensional atemverschiebliches Organ und ein häufiger Metastasierungsort kolorektaler Karzinome. Für die potenziell kurative Metastasenchirurgie spielt die exakte Bestimmung der Anzahl und Lokalisation von Metastasen eine wichtige Rolle. In Standardtechnik erfolgt die Akquisition…
Background/Objectives : Biliary complications are common after liver transplantation (LT), with bile leaks representing a major cause of morbidity. Conventional imaging modalities such as ultrasound, CT, MRCP, and endoscopic techniques may fail to localize peripheral or complex leaks. This study aimed…
Background: In addition to clinical examinations, confirmatory investigations are frequently performed to determine brain death (BD). Among other perfusion tests, brain perfusion scintigraphy (BPS) has been shown to be a reliable tool for the detection of brain circulatory arrest, particularly in cases…
Background The aim of this study was to investigate the preclinical biodistribution and molecular pathway of [ 68 Ga]Ga-BP-IDA and to evaluate its clinical suitability for quantitative monitoring of liver function during transarterial radioembolization (TARE) therapy of a hepatocellular carcinoma (HCC).…
Simple Summary Standardized ultrasound cine-loop video sequences can be seamlessly integrated into the clinical workflow, enabling the precise risk stratification of thyroid nodules via review in a PACS. The integration of additional cine loops into the clinical routine has been demonstrated to exhibit…
Diese nicht-interventionelle Beobachtungsstudie umfasst 41 Patienten und wertet die klinischen und technischen Aspekte der Behandlung der transarteriellen Radioembolisation mit Holmium-166-Mikrosphären aus. Die Kohorte umfasst 37 männliche Patienten und 4 weibliche Patientinnen mit Hepatozellulärem Karzinom…
Background/Objectives : The aim of this study was to evaluate the efficacy and accuracy of PET imaging and performance in defining the preoperative TNM classification, especially the intrathoracic lymph node staging, of patients with lung cancer. Methods : A retrospective, single-institution study of…
Patienten mit einem hepatozellulären Karzinom (HCC) haben in vielen Fällen eine schlechte Prognose, da kurative Therapien im fortgeschrittenen Stadium oft nicht mehr in Betracht kommen. Die selektive interne Radiotherapie (SIRT) ist als palliativer Therapieansatz verträglich und als Bridging-Therapie…
Hintergrund: Bei der Therapie des Mammakarzinoms stellt die Radiotherapie eine wichtige Säule dar. Da die manuelle Konturierung von Zielvolumina und Risikoorganen in der Bestrahlungsplanung sehr zeitaufwendig ist, kommen automatische Verfahren zum Einsatz. Eine Möglichkeit bietet atlasbasierte automatische…
The influence of the interventional treatment approach for transarterial radioembolization (TARE) on the incidence of extrahepatic microsphere depositions and to angiographic complications was evaluated. In total, 398 TARE cycles were analyzed. Interventional treatment approaches were classified as single…
Transarterial radioembolization (TARE) with 166 Ho-loaded microspheres is an established locoregional treatment for hepatocellular carcinoma (HCC), introduced in 2010. This study evaluates the clinical outcome of patients with HCC who underwent 166 Ho-TARE with personalized dosimetry. Twenty-seven patients…
In der vorliegenden Arbeit wurden präoperative 18F-FDG-PET/CT-Befunde von 104 Lungenkarzinompatienten, die innerhalb von zwei Jahren am Universitätsklinikum Jena operiert wurden, mit dem postoperativen histopathologischen Befund verglichen. Ziel war die Bestimmung der Genauigkeit der PET/CT bei der Erkennung…
We investigated transarterial radioembolization (TARE) as a palliative measure and bridging-to-transplant therapy in hepatocellular carcinoma (HCC) patients. A total of 167 patients (50 bridging, 117 palliative) with 245 TARE procedures were assessed. Fourteen patients underwent subsequent liver transplantation…
Die selektive interne Radiotherapie (SIRT) ist ein minimalinvasives Verfahren, welches bei der Behandlung primärer Lebertumore und bei Lebermetastasen eingesetzt werden kann. Bei der SIRT wird ein Katheter in der tumorversorgenden Leberarterie platziert, über den die Applikation radioaktiver Mikrosphären…
Purpose: Tumor boards serve as established platforms for interdisciplinary expert discussions and therapeutic recommendations tailored to individual patient characteristics. Despite their significance, medical students often lack exposure to such interdisciplinary discussions as tumor boards are currently…
Radionuclide cisternography (RNC) is a method for conducting imaging of the cerebrospinal system and can be used to identify cerebrospinal fluid leaks. So far, RNC has commonly employed radiopharmaceutical agents suitable only for single-photon emission tomography techniques, which are thus lacking in…
With the increasing use of next-generation sequencing, highly effective targeted therapies have been emerging as treatment options for several cancer types. Recurrent gene-fusions have been recognized in sarcomas; however, options for targeted therapy remain scarce. Here, we describe a case of a sarcoma,…
Holmium-166 microspheres are used for the transarterial radioembolization (TARE) treatment of primary and secondary liver cancers. In this study, its efficacy regarding local tumor control and integration into the oncological treatment sequence of the first 20 patients treated in our institution were…
Abstract Background Butylscopolamine (or hyoscine butylbromide, trade name Buscopan ® ) is occasionally administered as a premedication to reduce non-specific FDG uptake in the gastrointestinal tract based on its antiperistaltic effect. To date, there are no consistent recommendations for its use. The…