376 documents found

Dissertation
All rights reserved
2021

Effects of antifungals and long-term macrophage exposure on Candida species

Pathogenic fungi of humans and plants are an important, yet underestimated problem in the medical care system and in agriculture. Still, only few treatment options for human fungal infections are available today. In this work, a two-pronged approach was followed: A) Diversification of agriculturally...
Dissertation
CC BY-NC-SA 4.0
2021

Monitoring of methionine oxidation with fluorescent proteins

Methionine (Met) oxidation to methionine sulfoxide (MetO) is a post-translational protein modification that can appear unspecifically during exposure of Met to oxidants in normal growth and oxidative stress, such as occurring in aged organisms and in various degenerative diseases and pathologies. The...
Dissertation
CC BY 4.0
2021

Smoothness morrey spaces and differences : characterizations and applications

In his doctoral thesis the author studies the properties of Triebel-Lizorkin-Morrey spaces and Besov-Morrey spaces. For that purpose in a first step we prove characterizations in terms of higher order differences for those spaces. In connection with that we obtain sufficient and necessary conditions...
Dissertation
All rights reserved
2021

Manipulation der Materialeigenschaften von atomar abgeschiedenen Oxid-Dünnschichten...

Die vorliegende Arbeit beschäftigt sich mit der Entwicklung einer Methode zur Simulation der plasmaunterstützten Atomlagenabscheidung (engl.: plasma-enhanced atomic layer deposition, PEALD) mit elektrischem Feld. Der Schwerpunkt der Arbeit liegt in der Anwendung und Implementierung eines Monte-Carlo-(MC)-Simulationsschemas...
Dissertation
CC BY 4.0
2021

Aktivierung CD8α-charakterisierter γδ-T-Zellsubpopulationen bei verschiedenen...

Die γδ-T-Zellen stellen beim Huhn den Großteil der T-Zellen im Blut und Organen dar, was auf eine breitere funktioenlle Bedeutung in dieser evolutionär älteren Spezies hinweist. Es ist jedoch bisher nur wenig über ihre Aktivierung, Differenzierung und Funktionen bekannt. Ziel der vorliegenden Studie...
Dissertation
All rights reserved
2021

Toward quantum control in discrete-time quantum walks

Discrete-time quantum walks are among the branches of quantum information and computation. They are platforms for developing quantum algorithms for quantum computers. In addition, due to their universal primitive nature, discrete-time quantum walks have been used to simulate other quantum systems and...
Dissertation
CC BY 4.0
2021

Interactions of Candida albicans with non-pathogenic gut bacteria

The yeast Candida albicans is a commensal colonizer of mucosal surfaces in humans. Under certain circumstances, the fungus can cause superficial infections like oropharyngeal or vulvovaginal candidiasis, but also invasive and disseminated infections. Predispositions for this opportunistic pathogen to...
Dissertation
All rights reserved
2021

Optische und magnetische Eigenschaften Selten-Erd-dotierter Apatite

In this work REE3+-doped luminescent, magnetic and luminomagnetic apatite nanoparticles were synthesized and investigated with respect to their optical and magnetic properties and the resulting suitability as biomedical nanoparticle contrast agent. Investigations of the crystal chemical properties have...
Dissertation
CC BY-NC-ND 4.0
2021

Molecular kinetics of metabotropic glutamate receptors

Metabotropic glutamate receptors (mGluRs) belong to class C G-protein-coupled receptors (GPCRs). They are characterized by a large extracellular domain which is composed of the ligand-binding domain (LBD), followed by a cysteine rich-domain (CRD) that ends up at the transmembrane domains (TDM). After...
Dissertation
CC BY 4.0
2021

Einfluss von pränatalem Stress auf die fetale Gehirnentwicklung

Viele Frauen sind während der Schwangerschaft psychosozialem Stress ausgesetzt. Es ist bekannt, dass dies für den Fetus das Risiko für spätere neuropsychiatrische Auffälligkeiten erhöht. Bei der Stressübertragung auf den Fetus spielen erhöhte Cortisolspiegel eine große Rolle. Diese führen möglicherweise...
Dissertation
CC BY 4.0
2021

Überprüfung der Nachweisbarkeit eines tCSERP (trigeminalen chemosomatosensorischen...

Der Verlust des Riechempfindens führt zu starken Beeinträchtigungen, die sowohl im Alltag als auch im Beruf relevant werden können. Die Ursachen für Dysomien sind vielseitig und verbleiben trotz Anamnese, Untersuchung, Riechtestung sowie bildgebender Diagnostik häufig im Verborgenen. Gutachten werden...
Dissertation
CC BY 4.0
2021

Evaluation of treatment options for Enterococcus faecalis endocarditis...

Enterococcus faecalis is increasingly found as the causative organism of infective endocarditis, an infection of the heart valves with mortality rates up to 30 %. Traditionally, antibiotic combination therapy has been used for treatment of E. faecalis endocarditis, but it is still not clear if and which...
Dissertation
All rights reserved
2021

Artificial intelligence-based technologies for biophotonic data

For decades, biophotonic technologies have been booming in various fields of sciences. These technologies reveal not only structural but also molecular and functional changes in the sample under investigation. Additionally, they have prominent advantages such as high molecular sensitivity, high usability,...
Dissertation
All rights reserved
2021

Hybrid materials based on water-soluble polymers : preparation and application ...

This thesis describes the strategies for the innovative design of polymeric organic-inorganic hybrid materials using the development of synthetic approaches. The key objective of reported designs here is the excellent engineering of organic and inorganic building units that can successfully organize...
Dissertation
CC BY 4.0
2021

Untersuchung des Haftverbundes von PEEK zu Befestigungskompositen und vernetztem...

In der prothetischen Zahnheilkunde wird zunehmend die Gruppe der Polyaryletherketone (PAEKs) für Prothesen als Basiskunststoff verwendet. Für die ästhetische Verblendung werden herkömmliche Verblendkomposite und Verblendschalen verwendet. Die Haftfestigkeit von auf dem Markt verfügbaren Produkten wurde...
Dissertation
CC BY-NC-SA 4.0
2021

Metallopolymers towards sustainable applications

Metallopolymers feature a broad versatility in their properties due to the combination polymers and metal complexes resulting in numerous possible applications. Consequently, future challenges for a more sustainable society can be addressed by metallopolymers thus, they can be applied for self-healing...
Dissertation
All rights reserved
2021

Die soziale Integration der Sondersiedler in Westsibirien, 1945 bis Mitte...

Im Rahmen der Dissertation werden die grundlegenden Eigenschaften und Merkmale der Politik des stalinistischen Regimes in Bezug auf die Sondersiedlungen der Nachkriegszeit und die Reaktionen der Sondersiedler auf diese Politik analysiert. Untersucht werden sollen dabei im speziellen die Gründe, die unterschiedlichen...
Dissertation
CC BY 4.0
2021

Investigation of Class I jets with SOFIA

Protostellar outflows in form of highly collimated jets or less collimated winds are spectacular phenomena associated with star formation (Bally 2016; Frank et al. 2014). Through them excess angular momentum is transported away from the young forming star during its main accretion phase. Outflows are...
Dissertation
CC BY 4.0
2021

The mechanism and the ecological function of plant glucoside sequestration...

Many insect herbivores sequester (accumulate) plant defense metabolites in their bodies to utilize them for their own defense against natural enemies. In order to benefit from sequestered plant metabolites, an insect must take them up from the plant diet, avoid the metabolic breakdown to render them...
Dissertation
CC BY 4.0
2021

Approaching N = 1 Super-Yang-Mills theory with improved lattice actions

Investigations of the non-perturbative effects of N=1 Super-Yang-Mills theory on the lattice are demanding. The lattice breaks translation invariance to a discrete subgroup and consequently also supersymmetry. With a fine-tuning of the Wilson fermions to a critical point, it can be achieved that supersymmetry...

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