4 Dokumente gefunden

The ATLAS/NOA-29 study protocol: a phase III randomized controlled trial of anterior temporal lobectomy versus gross-total…

aus: BMC Cancer
Background: The discovery of cellular tumor networks in glioblastoma, with routes of malignant communication extending far beyond the detectable tumor margins, has highlighted the potential of supramarginal resection strategies. Retrospective data suggest that these approaches may improve long-term disease…
London: BioMed Central, 2025-02-20

Super-resolution of nodal and paranodal disruption in anti-pan-neurofascin-associated autoimmune nodopathy

Introduction: In autoimmune nodopathies, autoantibodies target the nodes of Ranvier, impairing saltatory nerve conduction. Understanding the impact of autoantibody binding on protein assembly is crucial for gaining insights into the pathogenicity of different autoantibodies. We investigated nodal, paranodal,…
Lausanne: Frontiers Media S.A., 2025-02-20

Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated…

Macrophage infectivity potentiator (MIP) proteins, found in pro- and eukaryotic pathogens, influence microbial virulence, host cell infection, pathogen replication, and dissemination. MIPs share an FKBP (FK506 binding protein)-like prolyl- cis/trans -isomerase domain, making them attractive targets for…
Washington, DC: American Chemical Society, 2025-02-20

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