000K utf8 1100 2024$c2024-11 1500 ger 2050 urn:nbn:de:gbv:27-dbt-68008-2 2051 10.1007/s12268-024-2339-y 3000 Klapper, Martin 3010 Ramm, Michael 3010 Stallforth, Pierre 4000 Naturstoffe aus der Vergangenheit [Klapper, Martin] 4060 3 Seiten 4209 Abstract Low molecular weight compounds biosynthesized by microorganisms, commonly known as natural products, are indispensable in modern medicine. They serve as the basis for many antibiotics, immunomodulators, and anti cancer agents. The new research field of paleobiotechnology allows access to natural products of the past. Based on ancient DNA from dental calculus, it was possible to generate bacterial natural products dating back over 100,000 years. 4950 https://doi.org/10.1007/s12268-024-2339-y$xR$3Volltext$534 4950 https://nbn-resolving.org/urn:nbn:de:gbv:27-dbt-68008-2$xR$3Volltext$534 4961 https://www.db-thueringen.de/receive/dbt_mods_00068008 5051 540 5051 570