000K utf8 1100 2024$c2024-02-29 1500 eng 2050 urn:nbn:de:gbv:27-dbt-20240418-140447-006 2051 10.3390/jpm14030264 3000 Böhle, Sabrina 3010 Finsterbusch, Luise 3010 Heinecke, Markus 3010 Kirschberg, Julia 3010 Matziolis, Georg 3010 Rohe, Sebastian 3010 Röhner, Eric 4000 Incidence of Secondary Osteoarthritis after Primary Shoulder and Knee Empyema and Its Risk Factors [Böhle, Sabrina] 4060 13 Seiten 4209 Empyema of the joint is an orthopedic emergency that is associated with a prolonged healing process despite adequate surgical and medical therapy. The risk of developing postinfectious osteoarthritis (OA) after successfully treated joint empyema is unknown. Both incidence and risk factors are important for prognostication and would therefore be clinically relevant for the selection of an adequate infectious therapy as well as for the individual follow-up of patients. The aim of this retrospective clinical study was to describe the risk of secondary OA after empyema based on knee and shoulder joint infections after successful primary infection treatment and its risk factors. Thirty-two patients were examined clinically and radiographically after completion of treatment for primary empyema of the knee or shoulder joint. Patients with previous surgery or injections in the affected joint were excluded from the study. The cumulative incidence of new-onset radiographic OA was 28.6%, representing a 5.5-fold increased risk of developing OA compared to the normal population. A figure of 25% of patients underwent total knee arthroplasty after knee empyema. Identified risk factors for primary empyema were obesity, hyperuricemia, and rheumatoid arthritis. Only about 60% of the patients tested positive for bacteria. Staphylococcus aureus, the most common pathogen causing joint empyema, was present in approximately 40% of cases. Secondary osteoarthritis, as a possible secondary disease after joint empyema, could be demonstrated and several risk factors for the primary empyema were identified. 4950 https://doi.org/10.3390/jpm14030264$xR$3Volltext$534 4950 https://nbn-resolving.org/urn:nbn:de:gbv:27-dbt-20240418-140447-006$xR$3Volltext$534 4961 https://www.db-thueringen.de/receive/dbt_mods_00060244 5051 610 5550 empyema 5550 joint empyema 5550 knee empyema 5550 postinfectious osteoarthritis 5550 secondary osteoarthritis 5550 septic arthritis 5550 shoulder empyema