000K  utf8
1100  2024$c2024-03-28
1500  eng
2050  urn:nbn:de:gbv:27-dbt-20240418-135734-004
2051  10.3390/ph17040437
3000  Werz, Oliver
3010  Seibel, Jens
3010  Stettler, Hans
3010  Theurer, Christoph
4000  The 125th Anniversary of Aspirin—The Story Continues  [Werz, Oliver]
4060  20 Seiten
4209  The year 2024 marks the 125th anniversary of aspirin, still one of the most frequently used drugs worldwide. Despite its veritable age, it is still relevant in pharmacotherapy and its use has spread to new areas over time. Due to aspirin’s multiple pharmacological actions unified in one single molecule (i.e., analgesic, antipyretic, anti-inflammatory, antithrombotic, and antiviral effects), it continues to attract considerable attention in the scientific community and is subject to intense basic and clinical research. In fact, recent results confirmed aspirin’s potential role as an antiviral drug and as an agent that can block harmful platelet functions in inflammatory/immunological processes. These features may open up new horizons for this ancient drug. The future of aspirin looks, therefore, bright and promising. Aspirin is not yet ready for retirement; on the contrary, its success story continues. This 125th anniversary paper will concisely review the various therapeutic uses of aspirin with a particular emphasis on the latest research results and their implications (e.g., use as an antiviral agent). In addition, the reader is provided with future perspectives for this remarkable drug.
4950  https://doi.org/10.3390/ph17040437$xR$3Volltext$534
4950  https://nbn-resolving.org/urn:nbn:de:gbv:27-dbt-20240418-135734-004$xR$3Volltext$534
4961  https://www.db-thueringen.de/receive/dbt_mods_00060142
5051  610
5550  acetylsalicylic acid
5550  anniversary
5550  antiviral
5550  aspirin
5550  future
5550  history