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Expression of LINC00174 in different cancers : Review of the literature and bioinformatics analyses

Affiliation
Department of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
Ghafouri-Fard, Soudeh;
Affiliation
Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
Safarzadeh, Arash;
Affiliation
Department of Clinical Analysis, College of Pharmacy, Hawler Medical University, Erbil, Kurdistan, Islamic Republic of Iraq
Hussen, Bashdar Mahmud;
GND
1249707153
ORCID
0000-0001-8381-0591
Affiliation
Institute of Human Genetics, Jena University Hospital, Jena
Taheri, Mohammad;
Affiliation
Anesthesiology Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
Eghbali, Ahmad

LINC00174 is an example of long intergenic non-coding RNAs with important functions in the development of human cancers. The gene encoding this lincRNA is located on 7q11.21. LINC00174 has been demonstrated to play an oncogenic role in a variety of cancers, including colorectal carcinoma, thymic carcinoma, glioma, glioblastoma, hepatocellular carcinoma, kidney renal clear cell carcinoma, breast cancer and non-functioning pituitary adenoma. In lung cancer, there is an obvious discrepancy between different studies regarding the role of this lincRNA. This lincRNA is also involved in the determination of prognosis of different cancers, particularly colorectal cancer. In the current review, we discuss the role of this lincRNA in human carcinogenesis based on the available data in the literature and bioinformatics tools.

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Category

Published in:
Pathology, research and practice
Vol. 248 (08.2023)Art.-No.:154617
Volume:
248
Date Issued:
08.2023
URN:
urn:nbn:de:gbv:27-dbt-20240326-080647-002
DOI:
10.1016/j.prp.2023.154617
Other identifier (pubmed):
37320864
Language:
English
Type of Resource:
Text
Extent:
8 Seiten
Publisher:
Elsevier BV
Keywords:
  1. Humans
    Typ
    Schlagwort
  1. Carcinoma, Hepatocellular
    Typ
    Schlagwort
  1. Carcinoma, Renal Cell
    Typ
    Schlagwort
  1. Liver Neoplasms
    Typ
    Schlagwort
  1. Thymus Neoplasms
    Typ
    Schlagwort
  1. Kidney Neoplasms
    Typ
    Schlagwort
  1. Computational Biology
    Typ
    Schlagwort
  1. Gene Expression Regulation, Neoplastic
    Typ
    Schlagwort
  1. RNA, Long Noncoding
    Typ
    Schlagwort
  1. Cancer
    Typ
    Schlagwort
  1. Lncrna
    Typ
    Schlagwort
  1. Linc00174
    Typ
    Schlagwort
DDC subject of DNB:
610 Medical sciences Medicine
Hosting institution:
Friedrich-Schiller-Universität Jena, Medizinische Fakultät
note:
Zweitveröffentlichung

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