Feasibility of a computerized cognitive training at patients with Mild Cognitive Impairment (MCI)

Mild Cognitive Impairment (MCI) is defined as a disorder characterized by (self-reported or externally reported) memory impairment, learning difficulties and reduced ability to concentrate for longer periods. Everyday functions are not severely impaired and the criteria for dementia are not fulfilled. However, the risk of progression to Alzheimer's dementia is approximately 10-15% per year in this group. A variety of computerized cognitive training programs (CCT) has been developed in recent years trying to reduce cognitive decline in healthy people and those at increased risk. Studies showed that memory performance could be improved by cognitive training even at older age and in MCI patients. However, no single study has so far targeted the question whether CCT is at all a feasible intervention for patients with MCI. In the thesis project, relevant criteria of objective and subjectively experienced feasibility of a CCT at the Memory Centre of the Neurology Department of the University Hospital Jena were analysed. Feasibility was assessed by recruitment, adherence, and dropout rate as well as reasons for drop-out and non-participation. In addition, participating patients were compared to patients who refused participation, as well as adhering patients to drop-out patients. Results showed that the most common reasons for non-participation were technical aspects. The comparison revealed that participating patients were significantly younger, higher educated and used technology more regularly. They felt significantly healthier overall but were also more concerned about their cognitive abilities and a progression to dementia. All in all, we found that CCT seems to be a feasible intervention for a wide range of patients. Yet, there are obstacles to be taken into account that hindered others from taking part. Therefore, wider studies are needed capturing the patients’ needs, capacities and wishes for training programs as well as the development of alternatives.

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