Leukemia : normal and malignant hemopoiesis

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1. 2023

   • Asciminib vs bosutinib in chronic-phase chronic myeloid leukemia previously treated with at least two tyrosine kinase inhibitors: longer-term follow-up of ASCEMBL

     p. 617

     Hochhaus, Andreas; Réa, Delphine; Boquimpani, Carla; Minami, Yosuke; Cortes, Jorge E.; Hughes, Timothy P.; Apperley, Jane F.; Lomaia, Elza; Voloshin, Sergey; Turkina, Anna; Kim, Dong-Wook; Abdo, Andre; Fogliatto, Laura Maria; le Coutre, Philipp; Sasaki, Koji; Kim, Dennis Dong Hwan; Saussele, Susanne; Annunziata, Mario; Chaudhri, Naeem; Chee, Lynette; García-Gutiérrez, Valentin; Kapoor, Shruti; Allepuz, Alex; Quenet, Sara; Bédoucha, Véronique; Mauro, Michael J.

   • Clinicohematologic and molecular response of essential thrombocythemia patients treated with pegylated interferon-α: a multi-center study of the German Study Group-Myeloproliferative Neoplasms (GSG-MPN)

     p. 924

     Stegelmann, Frank; Teichmann, Lino L.; Heidel, Florian H.; Crodel, Carl C.; Ernst, Thomas; Kreil, Sebastian; Reiter, Andreas; Otten, Sara; Schauer, Stefanie; Körber, Ruth-Miriam; Kricheldorf, Kim; Isfort, Susanne; Döhner, Hartmut; Brümmendorf, Tim H.; Griesshammer, Martin; Döhner, Konstanze; Koschmieder, Steffen

   • Response to the Comments from the Groupe Francophone de Cytogénétique Hématologique (GFCH) on the 5th edition of the World Health Organization classification of haematolymphoid tumors

     p. 1170

     Siebert, Reiner; Schuh, Anna; Ott, German; Cree, Ian A.; Du, Ming-Qing; Ferry, Judith; Hochhaus, Andreas; Naresh, Kikkeri N.; Solary, Eric; Khoury, Joseph D.

   • Genetic separation of chronic myeloid leukemia stem cells from normal hematopoietic stem cells at single-cell resolution

     p. 1561

     Chen, Yulin; Möbius, Susanne; Riege, Konstantin; Hoffmann, Steve; Hochhaus, Andreas; Ernst, Thomas; Rudolph, Karl Lenhard

   • The JAK1/2 inhibitor ruxolitinib in patients with COVID-19 triggered hyperinflammation: the RuxCoFlam trial

     p. 1879

     Hammersen, J.; Birndt, S.; Döhner, K.; Reuken, P.; Stallmach, A.; Sauerbrey, P.; La Rosée, F.; Pfirrmann, M.; Fabisch, Christian; Weiss, M.; Träger, K.; Bremer, H.; Russo, S.; Illerhaus, G.; Drömann, D.; Schneider, S.; La Rosée, P.; Hochhaus, A.

   • Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia

     p. 2027

     Eifert, Theresa; Hsu, Chen-Jen; Becker, Alicia L.; Graessle, Sarah; Horne, Arik; Bemmann, Franziska; Zhang, Qirui; Heuser, Michael; Vasioukhin, Valeri; Scholl, Sebastian; Hochhaus, Andreas; Siegerist, Florian; Endlich, Nicole; Bullinger, Lars; Lane, Steven W.; Haas, Simon; Schnoeder, Tina M.; Heidel, Florian H.

   • Survival with chronic myeloid leukaemia after failing milestones

     p. 2231

     Lauseker, Michael; Hehlmann, Rüdiger; Hochhaus, Andreas; Saußele, Susanne

   • Secondary-type mutations do not impact outcome in NPM1 -mutated acute myeloid leukemia: implications for the European LeukemiaNet risk classification

     p. 2282

     Eckardt, Jan-Niklas; Bill, Marius; Rausch, Christian; Metzeler, Klaus; Spiekermann, Karsten; Stasik, Sebastian; Sauer, Tim; Scholl, Sebastian; Hochhaus, Andreas; Crysandt, Martina; Brümmendorf, Tim H.; Krug, Utz; Wörmann, Bernhard; Hiddemann, Wolfgang; Görlich, Dennis; Sauerland, Cristina; Steffen, Björn; Einsele, Hermann; Neubauer, Andreas; Burchert, Andreas; Schäfer-Eckart, Kerstin; Berdel, Wolfgang E.; Schliemann, Christoph; Krause, Stefan W.; Hänel, Mathias; Hanoun, Maher; Kaufmann, Martin; Fransecky, Lars; Braess, Jan; Ruhnke, Leo; Schetelig, Johannes; Middeke, Jan Moritz; Serve, Hubert; Baldus, Claudia D.; Platzbecker, Uwe; Müller-Tidow, Carsten; Bornhäuser, Martin; Herold, Tobias; Thiede, Christian; Röllig, Christoph

   • Mutated IKZF1 is an independent marker of adverse risk in acute myeloid leukemia

     p. 2395

     Eckardt, Jan-Niklas; Stasik, Sebastian; Röllig, Christoph; Petzold, Andreas; Sauer, Tim; Scholl, Sebastian; Hochhaus, Andreas; Crysandt, Martina; Brümmendorf, Tim H.; Naumann, Ralph; Steffen, Björn; Kunzmann, Volker; Einsele, Hermann; Schaich, Markus; Burchert, Andreas; Neubauer, Andreas; Schäfer-Eckart, Kerstin; Schliemann, Christoph; Krause, Stefan W.; Herbst, Regina; Hänel, Mathias; Hanoun, Maher; Kaiser, Ulrich; Kaufmann, Martin; Rácil, Zdenek; Mayer, Jiri; Oelschlägel, Uta; Berdel, Wolfgang E.; Ehninger, Gerhard; Serve, Hubert; Müller-Tidow, Carsten; Platzbecker, Uwe; Baldus, Claudia D.; Dahl, Andreas; Schetelig, Johannes; Bornhäuser, Martin; Middeke, Jan Moritz; Thiede, Christian
2. 2022

   • The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms

     p. 1703

     Khoury, Joseph D.; Solary, Eric; Abla, Oussama; Akkari, Yassmine; Alaggio, Rita; Apperley, Jane F.; Bejar, Rafael; Berti, Emilio; Busque, Lambert; Chan, John K. C.; Chen, Weina; Chen, Xueyan; Chng, Wee-Joo; Choi, John K.; Colmenero, Isabel; Coupland, Sarah E.; Cross, Nicholas C. P.; De Jong, Daphne; Elghetany, M. Tarek; Takahashi, Emiko; Emile, Jean-Francois; Ferry, Judith; Fogelstrand, Linda; Fontenay, Michaela; Germing, Ulrich; Gujral, Sumeet; Haferlach, Torsten; Harrison, Claire; Hodge, Jennelle C.; Hu, Shimin; Jansen, Joop H.; Kanagal-Shamanna, Rashmi; Kantarjian, Hagop M.; Kratz, Christian P.; Li, Xiao-Qiu; Lim, Megan S.; Loeb, Keith; Loghavi, Sanam; Marcogliese, Andrea; Meshinchi, Soheil; Michaels, Phillip; Naresh, Kikkeri N.; Natkunam, Yasodha; Nejati, Reza; Ott, German; Padron, Eric; Patel, Keyur P.; Patkar, Nikhil; Picarsic, Jennifer; Platzbecker, Uwe; Roberts, Irene; Schuh, Anna; Sewell, William; Siebert, Reiner; Tembhare, Prashant; Tyner, Jeffrey; Verstovsek, Srdan; Wang, Wei; Wood, Brent; Xiao, Wenbin; Yeung, Cecilia; Hochhaus, Andreas

   • The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms

     p. 1720

     Alaggio, Rita; Amador, Catalina; Anagnostopoulos, Ioannis; Attygalle, Ayoma D.; Araujo, Iguaracyra Barreto de Oliveira; Berti, Emilio; Bhagat, Govind; Borges, Anita Maria; Boyer, Daniel; Calaminici, Mariarita; Chadburn, Amy; Chan, John K. C.; Cheuk, Wah; Chng, Wee-Joo; Choi, John K.; Chuang, Shih-Sung; Coupland, Sarah E.; Czader, Magdalena; Dave, Sandeep S.; de Jong, Daphne; Du, Ming-Qing; Elenitoba-Johnson, Kojo S.; Ferry, Judith; Geyer, Julia; Gratzinger, Dita; Guitart, Joan; Gujral, Sumeet; Harris, Marian; Harrison, Christine J.; Hartmann, Sylvia; Hochhaus, Andreas; Jansen, Patty M.; Karube, Kennosuke; Kempf, Werner; Khoury, Joseph; Kimura, Hiroshi; Klapper, Wolfram; Kovach, Alexandra E.; Kumar, Shaji; Lazar, Alexander J.; Lazzi, Stefano; Leoncini, Lorenzo; Leung, Nelson; Leventaki, Vasiliki; Li, Xiao-Qiu; Lim, Megan S.; Liu, Wei-Ping; Louissaint, Abner; Marcogliese, Andrea; Medeiros, L. Jeffrey; Michal, Michael; Miranda, Roberto N.; Mitteldorf, Christina; Montes-Moreno, Santiago; Morice, William; Nardi, Valentina; Naresh, Kikkeri N.; Natkunam, Yasodha; Ng, Siok-Bian; Oschlies, Ilske; Ott, German; Parrens, Marie; Pulitzer, Melissa; Rajkumar, S. Vincent; Rawstron, Andrew C.; Rech, Karen; Rosenwald, Andreas; Said, Jonathan; Sarkozy, Clémentine; Sayed, Shahin; Saygin, Caner; Schuh, Anna; Sewell, William; Siebert, Reiner; Sohani, Aliyah R.; Tooze, Reuben; Traverse-Glehen, Alexandra; Vega, Francisco; Vergier, Beatrice; Wechalekar, Ashutosh D.; Wood, Brent; Xerri, Luc; Xiao, Wenbin

   • Bosutinib versus imatinib for newly diagnosed chronic phase chronic myeloid leukemia: final results from the BFORE trial

     p. 1825

     Brümmendorf, Tim H.; Cortes, Jorge E.; Milojkovic, Dragana; Gambacorti-Passerini, Carlo; Clark, Richard E.; le Coutre, Philipp; Garcia-Gutierrez, Valentin; Chuah, Charles; Kota, Vamsi; Lipton, Jeffrey H.; Rousselot, Philippe; Mauro, Michael J.; Hochhaus, Andreas; Hurtado Monroy, Rafael; Leip, Eric; Purcell, Simon; Yver, Anne; Viqueira, Andrea; Deininger, Michael W.

   • Histone demethylase KDM4C is a functional dependency in JAK2 -mutated neoplasms

     p. 1843

     Ernst, Philipp; Schnöder, Tina M.; Huber, Nicolas; Perner, Florian; Jayavelu, Ashok Kumar; Eifert, Theresa; Hsu, Chen-Jen; Tubío-Santamaría, Nuria; Crodel, Carl C.; Ungelenk, Martin; Hübner, Christian A.; Clement, Joachim H.; Hochhaus, Andreas; Heidel, Florian H.

   • ASXL1 mutations predict inferior molecular response to nilotinib treatment in chronic myeloid leukemia

     p. 2242

     Schönfeld, Lioba; Rinke, Jenny; Hinze, Anna; Nagel, Saskia N.; Schäfer, Vivien; Schenk, Thomas; Fabisch, Christian; Brümmendorf, Tim H.; Burchert, Andreas; le Coutre, Philipp; Krause, Stefan W.; Saussele, Susanne; Safizadeh, Fatemeh; Pfirrmann, Markus; Hochhaus, Andreas; Ernst, Thomas

   • Modified risk-stratified sequential treatment (subcutaneous rituximab with or without chemotherapy) in B-cell Post-transplant lymphoproliferative disorder (PTLD) after Solid organ transplantation (SOT): the prospective multicentre phase II PTLD-2 trial

     p. 2468

     Zimmermann, Heiner; Koenecke, Christian; Dreyling, Martin H.; Pott, Christiane; Dührsen, Ulrich; Hahn, Dennis; Meidenbauer, Norbert; Hauser, Ingeborg A.; Rummel, Mathias J.; Wolf, Dominik; Heuser, Michael; Schmidt, Christian; Schlattmann, Peter; Ritgen, Matthias; Siebert, Reiner; Oschlies, Ilske; Anagnostopoulos, Ioannis; Trappe, Ralf U.

   • Impact of emerging ACA on survival in chronic myeloid leukemia (CML)

     p. 2544

     Hehlmann, Rüdiger; Lauseker, Michael; Voskanyan, Astghik; Fabarius, Alice; Haferlach, Claudia; Hochhaus, Andreas; Saußele, Susanne

   • Incidence of subsequent malignancies after total body irradiation-based allogeneic HSCT in children with ALL – long-term follow-up from the prospective ALL-SCT 2003 trial

     p. 2567

     Eichinger, Anna; Poetschger, Ulrike; Glogova, Evgenia; Bader, Peter; Basu, Oliver; Beier, Rita; Burkhardt, Birgit; Classen, Carl-Friedrich; Claviez, Alexander; Corbacioglu, Selim; Deubzer, Hedwig E.; Greil, Johann; Gruhn, Bernd; Güngör, Tayfun; Kafa, Kinan; Kühl, Jörn-Sven; Lang, Peter; Lange, Bjoern Soenke; Meisel, Roland; Müller, Ingo; Sauer, Martin G.; Schlegel, Paul-Gerhardt; Schulz, Ansgar; Stachel, Daniel; Strahm, Brigitte; Wawer, Angela; Peters, Christina; Albert, Michael H.
3. 2021

   • YBX1 mediates translation of oncogenic transcripts to control cell competition in AML

     p. 426

     Perner, Florian; Schnoeder, Tina M.; Xiong, Yijun; Jayavelu, Ashok Kumar; Mashamba, Nomusa; Santamaria, Nuria Tubio; Huber, Nicolas; Todorova, Kristina; Hatton, Charles; Perner, Birgit; Eifert, Theresa; Murphy, Ciara; Hartmann, Maximilian; Hoell, Jessica I.; Schröder, Nicolas; Brandt, Sabine; Hochhaus, Andreas; Mertens, Peter R.; Mann, Matthias; Armstrong, Scott A.; Mandinova, Anna; Heidel, Florian H.

   • Severe clinical relapse in an immunocompromised host with persistent SARS-CoV-2 infection

     p. 920

     Reuken, Philipp A.; Stallmach, Andreas; Pletz, Mathias W.; Brandt, Christian; Andreas, Nico; Hahnfeld, Sabine; Löffler, Bettina; Baumgart, Sabine; Kamradt, Thomas; Bauer, Michael

   • Enhanced differentiation of functional human T cells in NSGW41 mice with tissue-specific expression of human interleukin-7

     p. 3561

     Coppin, Emilie; Sundarasetty, Bala Sai; Rahmig, Susann; Blume, Jonas; Verheyden, Nikita A.; Bahlmann, Franz; Ravens, Sarina; Schubert, Undine; Schmid, Janine; Ludwig, Stefan; Geissler, Katharina; Guntinas-Lichius, Orlando; von Kaisenberg, Constantin; Groten, Tanja; Platz, Alexander; Naumann, Ronald; Ludwig, Barbara; Prinz, Immo; Waskow, Claudia; Krueger, Andreas

   • The impact of specific cytokine directed treatment on severe COVID-19

     p. 3613

     Reuken, P. A.; Rüthrich, M. M.; Hochhaus, A.; Hammersen, J.; Bauer, M.; La Rosée, P.; La Rosée, F.; Stallmach, A.
4. 2020

   • European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia

     p. 966

     Hochhaus, A.; Baccarani, M.; Silver, R. T.; Schiffer, C.; Apperley, J. F.; Cervantes, F.; Clark, R. E.; Cortes, J. E.; Deininger, M. W.; Guilhot, F.; Hjorth-Hansen, H.; Hughes, T. P.; Janssen, J. J. W. M.; Kantarjian, H. M.; Kim, D. W.; Larson, R. A.; Lipton, J. H.; Mahon, F. X.; Mayer, J.; Nicolini, F.; Niederwieser, D.; Pane, F.; Radich, J. P.; Rea, D.; Richter, J.; Rosti, G.; Rousselot, P.; Saglio, G.; Saußele, S.; Soverini, S.; Steegmann, J. L.; Turkina, A.; Zaritskey, A.; Hehlmann, R.

   • Frequently asked questions regarding SARS-CoV-2 in cancer patients—recommendations for clinicians caring for patients with malignant diseases

     p. 1487

     von Lilienfeld-Toal, Marie; Vehreschild, Jörg Janne; Cornely, Oliver; Pagano, Livio; Compagno, Francesca; Hirsch, Hans H.

   • Expert opinion—management of chronic myeloid leukemia after resistance to second-generation tyrosine kinase inhibitors

     p. 1495

     Hochhaus, Andreas; Breccia, Massimo; Saglio, Giuseppe; García-Gutiérrez, Valentín; Réa, Delphine; Janssen, Jeroen; Apperley, Jane

   • Holding CoVID in check through JAK?: The MPN-approved compound ruxolitinib as a potential strategy to treat SARS-CoV-2 induced systemic hyperinflammation

     p. 1723

     Heidel, F.; Hochhaus, A.

   • The Janus kinase 1/2 inhibitor ruxolitinib in COVID-19 with severe systemic hyperinflammation

     p. 1805

     La Rosée, F.; Bremer, H. C.; Gehrke, I.; Kehr, A.; Hochhaus, A.; Birndt, S.; Fellhauer, M.; Henkes, M.; Kumle, B.; Russo, S. G.; La Rosée, P.

   • Frequency of infections in 948 MPN patients: a prospective multicenter patient-reported pilot study

     p. 1949

     Crodel, Carl C.; Jentsch-Ullrich, Kathleen; Koschmieder, Steffen; Kämpfe, Dietrich; Griesshammer, Martin; Döhner, Konstanze; Jost, Philipp J.; Wolleschak, Denise; Isfort, Susanne; Stegelmann, Frank; Jilg, Stefanie; Hofmann, Verena; Auteri, Guiseppe; Rachow, Tobias; Ernst, Philipp; Brioli, Annamaria; von Lilienfeld-Toal, Marie; Hochhaus, Andreas; Palandri, Francesca; Heidel, Florian H.

   • Bosutinib for pretreated patients with chronic phase chronic myeloid leukemia:: primary results of the phase 4 BYOND study

     p. 2125

     Hochhaus, Andreas; Gambacorti-Passerini, Carlo; Abboud, Camille; Gjertsen, Bjørn Tore; Brümmendorf, Tim H.; Smith, B. Douglas; Ernst, Thomas; Giraldo-Castellano, Pilar; Olsson-Strömberg, Ulla; Saussele, Susanne; Bardy-Bouxin, Nathalie; Viqueira, Andrea; Leip, Eric; Russell-Smith, T. Alexander; Leone, Jocelyn; Rosti, Gianantonio; Watts, Justin; Giles, Francis J.

   • The EUTOS long-term survival (ELTS) score is superior to the Sokal score for predicting survival in chronic myeloid leukemia

     p. 2138

     Pfirrmann, Markus; Clark, Richard E.; Prejzner, Witold; Lauseker, Michael; Baccarani, Michele; Saussele, Susanne; Guilhot, François; Heibl, Sonja; Hehlmann, Rüdiger; Faber, Edgar; Turkina, Anna; Ossenkoppele, Gert; Höglund, Martin; Zaritskey, Andrey; Griskevicius, Laimonas; Olsson-Strömberg, Ulla; Everaus, Hele; Koskenvesa, Perttu; Labar, Boris; Sacha, Tomasz; Zackova, Daniela; Cervantes, Francisco; Colita, Adriana; Zupan, Irena; Bogdanovic, Andrija; Castagnetti, Fausto; Guilhot, Joëlle; Hasford, Joerg; Hochhaus, Andreas; Hoffmann, Verena S.

   • Prevalence and dynamics of clonal hematopoiesis caused by leukemia-associated mutations in elderly individuals without hematologic disorders

     p. 2198

     Midic, Danica; Rinke, Jenny; Perner, Florian; Müller, Violetta; Hinze, Anna; Pester, Frank; Landschulze, Jürgen; Ernst, Jana; Gruhn, Bernd; Matziolis, Georg; Heidel, Florian H.; Hochhaus, Andreas; Ernst, Thomas

   • SIRT7: an influence factor in healthy aging and the development of age-dependent myeloid stem-cell disorders

     p. 2206

     Kaiser, Alexander; Schmidt, Martin; Huber, Otmar; Frietsch, Jochen J.; Scholl, Sebastian; Heidel, Florian H.; Hochhaus, Andreas; Müller, Jörg P.; Ernst, Thomas