000K utf8 1100 2021$c2021-09 1500 eng 2050 urn:nbn:de:gbv:27-dbt-20230325-014401-000 2051 10.1007/s00423-021-02206-9 3000 Felgendreff, Philipp 3010 Aschenbach, René 3010 Dondorf, Felix 3010 Lux, Sascha 3010 Rauchfuss, Falk 3010 Settmacher, Utz 3010 Tautenhahn, Hans-Michael 4000 Simultaneous right-sided nephrectomy with orthotopic liver and kidney transplantation:$dAn alternative method for patients with autosomal dominant polycystic liver and kidney disease [Felgendreff, Philipp] 4060 9 Seiten 4209 Purpose: In patients suffering from autosomal dominant polycystic liver and kidney disease (ADPLKD), combined organ transplantation often poses a technical challenge due to the large volume of both organs. To simplify the transplantation procedure by improving the exposure of anatomical structures, we introduce a novel surgical technique of orthotopic liver and kidney transplantation. Methods: The modified simultaneous liver and kidney transplantation technique via a right-sided L-incision included three steps: (1) right-sided nephrectomy in the recipient followed by (2) orthotopic liver transplantation in cava replacement technique and (3) the orthotopic kidney transplantation with arterial reconstruction to the right common iliac artery. Results In total, seven patients with ADPLKD were transplanted by using the modified transplantation technique. The mean operation time was 342.43 min (±68.77). Postoperative patients were treated for 6.28 days (±2.50) in the intensive care unit and were discharged from the surgical ward approximately 28 days (±5.66) after the operation with normal graft function. Complications associated with the use of the modified technique, such as bleeding, anastomotic stenosis, biloma, or urinoma, did not occur. Conclusion: Modified simultaneous liver and kidney transplantation is a safe alternative for patients with ADPLKD. By combining right-sided nephrectomy and orthotopic graft transplantation, the approach optimizes the exposure of anatomical structures and simplifies the transplantation procedure. Additionally, the modified transplantation technique does not require a particular organ explantation procedure and can be applied for all liver and kidney grafts. 4950 https://doi.org/10.1007/s00423-021-02206-9$xR$3Volltext$534 4950 https://nbn-resolving.org/urn:nbn:de:gbv:27-dbt-20230325-014401-000$xR$3Volltext$534 4961 https://www.db-thueringen.de/receive/dbt_mods_00056294 5051 610 5550 Autosomal dominant polycystic liver and kidney disease 5550 Kidney transplantation 5550 Liver transplantation