There are many different approaches to simulate the mechanical behavior of RC−Frames with masonry infills. In this paper, selected modeling techniques for masonry infills and reinforced concrete frame members will be discussed − stressing the attention on the damaging effects of the individual members and the entire system under quasi−static horizontal loading. The effect of the infill walls on the surrounding frame members is studied using equivalent strut elements. The implemented model consider in−plane failure modes for the infills, such as bed joint sliding and corner crushing. These frame member models differ with respect to their stress state. Finally, examples are provided and compared with experimental data from a real size test executed on a three story RC−Frame with and without infills. The quality of the model is evaluated on the basis of load−displacement relationships as well as damage progression.